1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene - Names and Identifiers
Name | 1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene
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Synonyms | S,S-Et-Ferrocelane 1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene 1,1'-Bis[(2S,5S)-2,5-diethyl-1-phospholanyl]ferrocene carbanide,(2S,5S)-1-cyclopentyl-2,5-diethylphospholane,iron(2+)
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CAS | 436863-50-2
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1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene - Physico-chemical Properties
Molecular Formula | C26H40FeP2
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Molar Mass | 470.39 |
Melting Point | 89-91°C |
Appearance | solid |
Color | yellow |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | air sensitive |
Physical and Chemical Properties | Optical rotation (optical activity) [α]20/D -382 °, c = 1 in chloroform |
1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene - Risk and Safety
1,1′-Bis[(2S,5S)-2,5-diethylphospholano]ferrocene - Introduction
1,1 '-BIS [(2S,5S)-2,5-diethylphosphinoalkyl] Ferrocene is an organic compound with the molecular formula C26H38FeP2 and a molecular weight of 503.38. It is a dark red crystal, soluble in some organic solvents, such as toluene and methylene chloride.
The main use of this compound is as a chiral catalyst for asymmetric catalysis in organic synthesis reactions. It is widely used in asymmetric hydrogenation, Asymmetric oxidation, asymmetric hydroxyamide synthesis and other reactions. Its chiral structure can make the enantioselectivity better, which is helpful for the synthesis of chiral molecules.
1,1 '-BIS [(2S,5S)-2,5-diethylphosphinoalkyl] Ferrocene is usually prepared by mixing 2, the 5-diethylphosphinoalkanol is obtained by reaction with sodium Di (ferrocene) dimethyl. After this step, the target product can be obtained by acid treatment and crystallization purification.
When using and handling 1,1 '-BIS [(2S,5S)-2,5-diethylphosphinoalkyl] ferrocene, safety precautions should be paid attention. It is an organic compound and should avoid violent reactions with strong oxidants and strong acids. Care should be taken to prevent inhalation, ingestion or contact with skin. Wear appropriate protective equipment, such as gloves, glasses and protective clothing, if necessary.
In General, 1,1 '-BIS [(2S,5S)-2,5-diethylphosphinoalkyl] ferrocene has important catalytic applications, especially for the synthesis of chiral compounds. However, it is necessary to pay attention to safe operation during use.
Last Update:2024-04-10 22:29:15